REGENERATIVE BIOLOGY AND DISEASE**Pay attention to the marking scheme! ~0.5 marks per clear point
1. Your mom’s great aunt Mable tells you that she is part of a cutting edge study where she injects squirrel stem
cells into her face to reduce wrinkles, based on what you are learning in this course what would you say to
her? (8 marks)
2. A friend of yours learned that you were taking this class and asked why worms can regenerate when cut in
half and humans can’t. From what you have learned so far what is your response to this? (8 marks) What
are some steps that you would take to figure out if you were right? (6 marks).
3. You are a famous scientist working on a cure for spinal cord injury. You decide you will use ESCs to make the
neurons that are damaged in these patients.
a. From what you have learned in class so far what are some strategies that you would take to
accomplish this? (20 marks)
b. Your experiment fails from the very beginning – what can go wrong at the very earliest stages? (4
marks)
4. You LOVE signaling pathways and are so thrilled to be learning so many of them in this course! Why is it
important to understand the molecular details about signaling pathways to understanding regenerative biology??
(5 marks)
5. You are playing soccer and twist your ankle – your coach yells out for you to put ice on it right away. Why
might this be an important bit of advice for you as a budding superstar soccer player? (3 marks)
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